Search results for "Network connectivity"
showing 6 items of 6 documents
Dissemination protocol for Heterogeneous Cooperative Vehicular Networks
2012
International audience; The difficulties associated with network connectivity, unreliable channels, and city environment characteristics make data dissemination task in vehicular urban networks a real challenge. Recently, some interesting solutions have been proposed to perform data dissemination in this environment. Starting from the analysis of these solutions, we present a new dissemination protocol named DHVN (Dissemination protocol for Heterogeneous Cooperative Vehicular Networks) that considers: (i) roads topology, (ii) network connectivity and possible partitioning in case of low traffic density, and (iii) heterogeneous communication capabilities of the vehicles. We compare our proto…
The role of network connectivity on epileptiform activity.
2021
AbstractA number of potentially important mechanisms have been identified as key players to generate epileptiform activity, such as genetic mutations, activity-dependent alteration of synaptic functions, and functional network reorganization at the macroscopic level. Here we study how network connectivity at cellular level can affect the onset of epileptiform activity, using computational model networks with different wiring properties. The model suggests that networks connected as in real brain circuits are more resistant to generate seizure-like activity. The results suggest new experimentally testable predictions on the cellular network connectivity in epileptic individuals, and highligh…
Data Backup Dilemma
2016
When the Great East Japan Earthquake struck in 2011, several municipalities lost their residential data including backup. Since none of them had ever considered the total loss of data, data backup policy had been paid little attention. In many cases, the backup tapes were simply stored inside the server room, just beside the server rack. Following the calamity, the Japanese national government tried to introduce a data backup system to municipalities using the cloud. The purpose was to secure the safekeeping of backup data. However, municipalities were reluctant to go along with this since overcoming the loss of network connectivity during an earthquake remained foremost in their minds. The…
Energy-Efficient Protocol Design
2015
Recent studies have shown that the total energy consumed by the Internet has followed an increasing trend over the years. A considerable part of this energy is wasted due to an inefficient utilization of edge devices , that is, Personal Computers (PCs) and other user equipment in homes and offices. PCs are often left on even when they are not used (e.g., overnight or during weekends), while other edge devices, such as printers, IP phones, and displays, are typically kept always on , especially in public buildings. A number of solutions have been proposed for eliminating, or reducing, energy wastes caused by edge devices. In this chapter, we propose a general taxonomy for their classificatio…
Alterations in White Matter Network and Microstructural Integrity Differentiate Parkinson’s Disease Patients and Healthy Subjects
2019
Parkinson’s disease (PD) is a neurodegenerative disease, neuropathologically characterized by progressive loss of neurons in distinct brain areas. We hypothesize that quantifiable network alterations are caused by neurodegeneration. The primary motivation of this study was to assess the specific network alterations in PD patients that are distinct but appear in conjunction with physiological aging. 178 subjects (130 females) stratified into PD patients, young, middle-aged and elderly healthy controls (age- and sex-matched with PD patients), were analyzed using 3D-T1 magnetization-prepared rapid gradient-echo (MPRAGE) and diffusion weighted images acquired in 3T MRI scanner. Diffusion modeli…
Auxiliary α2δ1 and α2δ3 Subunits of Calcium Channels Drive Excitatory and Inhibitory Neuronal Network Development
2020
VGCCs are multisubunit complexes that play a crucial role in neuronal signaling. Auxiliary α2δ subunits of VGCCs modulate trafficking and biophysical properties of the pore-forming α1 subunit and trigger excitatory synaptogenesis. Alterations in the expression level of α2δ subunits were implicated in several syndromes and diseases, including chronic neuropathic pain, autism, and epilepsy. However, the contribution of distinct α2δ subunits to excitatory/inhibitory imbalance and aberrant network connectivity characteristic for these pathologic conditions remains unclear. Here, we show that α2δ1 overexpression enhances spontaneous neuronal network activity in developing and mature cultures of …